You have done everything right. You tried the medications, you waited the weeks, you switched and tried again. And the heaviness is still there. When antidepressants have not given you your life back, ketamine therapy for depression offers a different mechanism and, for many people, relief that arrives in hours or days rather than weeks.
80%
of treatment resistant depression patients we treat see measurable relief
Hours to days
To first relief for many patients, not weeks
45 minutes
Per ketamine session, with a 2 hour private suite reserved for you
2 hours
Of integration coaching included with every plan
FDA approved
Spravato nasal spray available as an option
Depression is not just sadness. It is the slow draining of color from things that used to matter. Some days it is heavy and still. Other days it is restless and raw. It can hide behind a normal looking life.
Symptom domain
Mood
Energy
Interest
Sleep
Focus
Self worth
Body
Common impact on daily life
Persistent low mood, emptiness, or a sense that nothing will improve
Exhaustion that sleep does not fix, simple tasks feel enormous
Hobbies, people and food lose their pull, joy goes flat
Sleeping too much or lying awake at 3 in the morning
Decisions stall, thoughts feel foggy, work piles up
Harsh inner voice, guilt, feeling like a burden
Aches, appetite changes, slowed movement and speech
When depression persists despite two or more adequate medication trials, it is often classed as treatment resistant, and ketamine becomes a medically appropriate next step.
Most antidepressants work slowly on serotonin and affect your whole system, which is why side effects pile up while you wait for results. Ketamine works differently. It acts on the glutamate system and the NMDA receptor, which helps the brain produce more brain derived neurotrophic factor and form new connections. Think of it less like topping up a chemical and more like helping the brain rewire the circuits that depression has worn down.
That is why relief can come quickly. For some, a single infusion lasts a week or longer. After a short series, the effect often extends for weeks to months. Every infusion is administered and overseen by an anesthesia provider, with no anesthesia required, and you rest in a private suite the whole time.
A typical plan is a short series of sessions over a few weeks, followed by boosters as needed. Each session is about 45 minutes, and your suite is reserved for two hours so you are never rushed.
01
Call (954) 320-4944 or request a consultation online. We review your history and goals.
02
We confirm ketamine is a safe fit and coordinate a psychiatrist or primary care referral.
03
You recline in a private suite while a nurse practitioner administers and monitors your treatment.
04
Two hours of integration coaching are included.
05
Many patients return for occasional booster sessions to hold their progress.
Feature
How it works
Invasiveness
Common side effects
Works when meds fail
Treatment time
Insurance coverage
Ketamine
Ketamine acts on the brain’s glutamate system and blocks NMDA receptors, setting off a cascade that promotes neuroplasticity and the growth of new neural connections. This is a different pathway from traditional antidepressants, which work mainly on serotonin.
Yes, this is its main use
SSRIs and SNRIs
Medication changes brain chemistry body wide
Oral medication
Weight, sleep, sexual, and energy effects
Often the thing that already failed
Daily pill
Widely covered
Therapy (CBT)
Talk therapy reshapes thoughts and behavior
Noninvasive
None physical
Sometimes, varies by person
Weekly sessions
Often covered
ECT
Electrical current induces a brief seizure
Requires anesthesia
Memory effects, recovery time
Yes, but more intensive
Multiple sessions with recovery
Covered, used for severe cases
Transcranial Magnetic Stimulation (TMS) is a non-invasive, drug-free treatment that uses gentle magnetic pulses to stimulate the areas of the brain linked to mood. It needs no anesthesia and has no downtime, and it is covered by most major insurance plans. Many patients choose TMS on its own or alongside ketamine for lasting relief from depression.
Coverage for ketamine, Spravato and TMS continues to expand, and most major insurances are accepted. We also accept FSA, HSA, all major credit cards and the Advance Care Card. Our team helps verify your benefits before you begin.
For people whose depression has not responded to antidepressants, ketamine offers a different mechanism that often works when medications have not. Many patients use both as part of a broader plan.
Many patients feel relief within hours or days. A single infusion may last a week or longer, and a short series often extends the effect for weeks to months.
Most patients do not experience worsening. Your care team monitors you closely and adjusts your plan as needed.
Often yes. Never stop or change a medication on your own. We coordinate with your prescriber so your plan stays safe.
Plans vary, but a short initial series followed by occasional boosters is common. We tailor it to your response.
An anesthesia provider administers and oversees every infusion. We are led by two certified nurse anesthesiologists, and safety is built into every step.
We can help. We work with local psychiatrists and can share telemedicine or in person options to complete your referral.
Contact us today and learn how Ketamine Clinic can guide your personal wellness journey.
By Appointment Only
41 N Federal Hwy, Suite A, 2nd Floor Pompano Beach, FL 33062
(954) 320-4944
(954) 400-5805
contact@ketamineclinicsouthflorida.com
